- Captain Flash:
- The Mirror Man is an interdimensional being that feeds on the silicon of his victims, seeking to devour all of the Earth's most brilliant minds. Having the power to travel through mirrors, the Mirror Man makes his debut murdering a scientist who's experiments brought him to Earth and proceeds to do the same to another. He then tries to kill the father of Ricky Davis, Captain Flash's sidekick, until he was foiled by the heroes. Returning to devour all of the scientists in a conference, he kidnaps Dr. Mitchell and kills him before doing the same to another victim. The Mirror Man infiltrates the conference to slaughter everyone there and feast on their silicon until they're nothing but a dried husk. All while taking sadistic pleasure in taunting his arch-foe every failed attempts in stopping him.
- "The Iron Mask": The Iron Mask is a madman who seeks to steal the radioactive Cobalt so he could make a profit off of it. He uses Criminal Mind Games based on the story of Odysseus to lure his foe, Captain Flash, and face his robotic replicas of Greek monsters. All while threatening to use a hydrogen bomb filled with radiation to blow up all of Atom City as distraction.
- "The Fight of the Century": Muscle Man, also known as Muscles, is a muscle-for-hire working for the Mob who is given Super-Strength by a mob boss. Aiding criminals in several heists and robberies, Muscle sabotages a train using a boulder to rob it of its wealth. Not showing concerns over the fact that hundreds of innocent people would perish upon crashing onto another train, Muscle Man accepts Captain Flash's challenge in combat hoping to tear him limb from limb.
- "The Invaders": Mirago is the king of Imago seeking to conquer the Earth after his own planet is dying. Only caring about ruling the planet than simply saving his people from destruction, Mirago plans to infiltrate human society by having his minions disguise as world leaders to sow hatred and discord among the people of Earth. Once this succeeds, he would have the humans destroy each other prompting him to swoop in and takeover the planet.
- Cerebex (Planet Comics): Cerebex, once a European dictator named Schmackenberg, is a megalomaniac hellbent on world conquest. Faking his suicide under a bunker, he performs experiments on his daughter in hopes of storing his brain onto her body to preserve his life. Once this fails, he has his scientist Walter Jackson construct a machine for his plans, only to have his brain stored in said machine of which he promptly kills Walter. Using his new mechanical body to go on a rampage across the country with his army of robots, laying waste the country as his army sends cities to ruins and slaughtering the army in his way. He sends his robots to assassinate world leaders that would pose as an obstacle for his conquest.
- Lady Styx is an insectoid conqueror who dreams of reducing all life in the universe to undead slaves who worship her. Created when proud aliens tried to combine their intelligence in order to enslave neighboring planets, Styx embraces their vain vision and works to spread the hero Stygian virus, reducing those infected to her slaves. Her crusade leaves countless worlds, including the whole Sector 3500, destroyed by her fleet and their inhabitants reduced to zombies or Human Resources for her to use. She puts a bounty on the heads of heroes who stood in the center of the universe, planning to dissect them and learn secrets they saw. After getting trapped in the dimension of dark matter, she sends her missionary Darkstars to the Vega system to establish a religion worshiping her there, slaughtering most of the Omega Men and their allies when they refused to worship her. Styx searches for Heartstones, which would give her power to become a god, sending the Spider Guild on Earth to destroy a city and kidnap thousands of people in a search for one Heartstone. She manipulates hosts of stones in freeing herself and becoming the heart for her new body as she almost absorbs the whole universe. Styx is revealed to have infected Animal Man with a virus that turns those it infects into her violent worshipers to continue her work in case she is defeated. She returns to continue her crusade, razing the planet Kranaltine and enslaving its people.
- Xena Warrior Musical The Lost Scroll: Kako is the leader of a gang of bandits who fancies himself a warlord. Wanting to make a profit, Kako often raids villages to take their valuables and sell them. When he finds out about the Amazonian artifact The Bow of Artemis, he kidnaps the Amazonian queen Ephiny and her heir Myrina, and has his men hold Ephiny at knifepoint to coerce Myrina into helping them get into the cave the Bow is held in, and stabs her anyway when Myrina agrees. Upon finally getting the Bow, he orders his men to massacre the Amazons.
- Little House on the Prairie's "Sylvia": Irv Hartwig is the darkest villain to ever step into Walnut Grove. A seemingly-friendly blacksmith, Hartwig masks the fact that he is a child predator who commits his crimes while wearing a clown mask. Selecting young Sylvia as his latest target, Hartwig attacks and rapes the girl in the woods, then pretends to be a friend to her traumatized family. When he learns that Sylvia is pregnant from the attack and planning to run away from town, Hartwig tries to rape her again, then kill her and her crush Albert. Though Hartwig is shot dead before he can succeed, Sylvia suffers such severe injuries from Hartwig's latest attack that she dies soon after.
- You (2018): Season 2: Joshua "Henderson" Bunter is a Serial Rapist who uses his status as a famous stand-up comedian to gain the trust of adolescent girls, before taking them to his home, where he would then drug them before raping them while they are unconscious. He would also take photos of his victims, revealing to have claimed many victims through the number of pictures he had. Henderson had also raped Joe Goldberg's neighbor, Delilah Alves, and attempted to rape Delilah's younger sister, Ellie, after drugging her.
- Resident Evil: The Final Chapter novelization by Tim Waggoner:
- Alexander Roland Isaacs is the primary shareholder of Umbrella Corporation and the true mastermind behind the T-Virus pandemic. After an attempt at mass marketing the Protenitor Cell causes a small outbreak in Cape Town, Isaacs has his subordinate Albert Wesker murder the kind hearted Dr. James Marcus when he shows concern about the danger of the virus. After redefining the Progenitor Cell into the T-Virus, Isaacs gains delusions of godhood in the following decade and then releases the pathogen at large, causing the undead to overrun the world and decimate humanity. Having opted to freeze himself and other Umbrella top executives to wait out the apocalypse and then rebuild the world in his own vision, Isaacs leaves Wesker in charge of operations, allowing him to reduce the remaining world population to less than 4500 people worldwide. Awaking from his cryoslumber when Alice infiltrates the Hive, Isaacs sadistically reveals the truth about her being a clone and promises to get rid of her template once the surface is purged of life. After the tables are turned on him, Isaacs abandons his allies to die and, during his fight with Alice, slices her fingers off with a laser beam. Having survived his apparent death, Isaacs makes his way to the surface and verbally dismisses his own clone before trying to kill Alice one final time.
- Albert Wesker is the high-ranking Umbrella employee and the top subordinate of Dr. Alexander Isaacs. Having murdered Dr. James Marcus upon Isaacs' orders, Wesker then assists Isaacs in his experiments and then his plan to purge humanity. Taking control of the corporation while Isaacs and the rest are frozen, Wesker proceeds to carry out the cleanup operation along with Isaacs' clones until the human population is almost completely extinct. After rescuing Alice from Umbrella Prime, Wesker injects her with a temporary strain of T-Virus and lures her and her allies into a trap at the White House in order to take down his Umbrella rival, Dania Cardoza. Refusing Cardoza's offer to leave peacefully, Wesker shows no care when his allies die when Cardoza unleashes Melange in retaliation. Once Alice's powers are expended, Wesker beats her down and fatally stabs Jill Valentine through the eye with his infected tentacle before attempting to feed Alice herself to Melange. After devouring the real Cardoza once back at the Hive, Wesker keeps track of Alice though Red Queen; when she infiltrates the facility, he takes control of the Hive's defence system and kills most of her group with various traps. Despite being defeated, Wesker survives in the cellular form miles beneath the Hive, planning to resurface once the antivirus has run its course.
- The second clone of Alexander Isaacs was put in charge of leading extermination campaign against the survivors, but over time his religious beliefs eclipsed those of his original self. Capturing any lone survivors he can find, the clone subjects them to humiliation and abuse for being "sinners", even trying to molest a captured woman several times and cutting off the tongue of another prisoner when he tries to intervene. When Alice falls into his trap, the clone Isaacs shows the heads of Alice's clones he killed in the past before interrogating Alice herself by forcing her to run from the undead while tied up to the tank's rear, something he had done to many others before her with all of them dying. When Alice breaks free and escapes, the clone tortures his prisoners and kills all but three of them, one of whom he sacrifices during the siege of Raccoon City settlement later on. After being defeated once more, Isaacs becomes so deranged he stabs another tank commander to death upon his order being refused, causing the rest of the crew to desert him. Leading the undead army to the Hive, the clone Isaacs murders his real self in a fit of rage before trying to do the same with Alice.
- What If Anakin Skywalker Started A Jedi Civil War (link
): Palpatine, seeing that outcome of Anakin's uprising against the Jedi and his subsequent reforms to the Jedi Order threatens to end the Clone Wars and his bid for absolute power, seeks to sabotage peace negotiations between the Republic and the Separatists. Following a failed attempt by General Grievous to sabotage the peace negotiations, Palpatine would send Dooku to use his political influence within the Confederacy to subvert peace negotiations from within, while trying to stoke lingering resentments Anakin still has with the surviving Jedi that sided with Yoda during his uprising. When Anakin proves incorruptable, he tries to turn public opinion against both the Jedi and the peace negotiations. Forced to flee into hiding when all these plans fail, Palpatine prepares one final attempt to turn Anakin to the dark side by planning Padme's murder. - Transformers: Deviations: Unicron is a terrifying gargantuan Transformer who devours planets and any living creatures on them, having been responsible for the destruction of the planet Lithone, leaving an individual named Kranix as the sole survivor. Making a deal with the new Decepticon leader Starscream by sending him after the Matrix of Leadership and turning him into Megascream, Unicron later turns on the Decepticon by going after Cybertron and its moons.
- Warcraft: Yogg-Saron is the Old God of Death, and he proves himself to be every bit as vile as his rival N'Zoth. Forming the Black Empire with the other Old Gods, Yogg-Saron would last longer than his rivals and had his C'thraxxi minions slaughter many Titanforged before he was finally locked away in the prison city of Ulduar. While imprisoned, Yogg-Saron would take advantage of Keeper Loken having an affair with Keeper Thorim's wife Sif, Yogg-Saron tricked him into killing Sif, and got him to start a war between Thorim and his Frost Giant allies while Yogg-Saron corrupted the Forge of Wills with the Curse of Flesh to make Titanforged easier to corrupt while also tainting the world tree Vordrassil and creating the Emerald Nightmare, all the while enslaving his jailers and getting Loken to manipulate himself into the position of Prime Designate, assuring that the death of Yogg-Saron's foremost pawn would usher in the death of all life on Azeroth.
- Zero Visibility: "God" is a cosmic horror who drains the life from entire planets and their populations to satisfy itself. When the only survivors of the last race it scoured seal it away within a Place Beyond Time, "God" reaches out to hundreds of innocent humans and lures them to its seal in an effort to suck the life from them and regain its strength. Although eldritch to the point of having no intelligence dialogue, "God" is evincibly cruel and deliberate in its actions. Old murals depicting it sparing some of the aliens it devoured simply so they could serve it as broken slaves, and it plays on the grief of the Sole Survivor of the latest traveling party it's lured to have her murder its alien jailer, resulting in it devouring her and breaking free to resume its cosmic rampage, starting with Earth.
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To Be Created
