Serenity may refer to:
- Dissonant Serenity, a trope about characters maintaining a calm and composed demeanor in dire and stressful situations.
- Serenity, an Austrian symphonic Power Metal band.
- Serenity, a OEL Manga written by Buzz Dixon.
- Serenity Rose, a 2002 webcomic written by Aaron Alexovich
- Serenity, another name for the Firefly franchise, used in works such as....
- Serenity (2019), a little-seen mystery thriller film starring Matthew McConaughey and Anne Hathaway.